Job Description

Thelaboratory of the Department of Dermatology is focused on the study of human Thelper cells and their role in inflammatory skin disease. We aim to betterunderstand the mechanisms of skin inflammation and to create new therapeuticstrategies.

What you can expect

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Skin T cells play a central role in protecting the body, but their dysregulated activation drives chronic inflammatory skin disease. Current treatments suppress inflammation, yet rarely provide long-term cure. To develop curative therapies, we need to understand the upstream mechanisms that sustain inflammation, such as the interleukin-18 (IL-18) pathway.

Recent findings suggest that IL-18 plays a crucial role in atopic dermatitis (AD). Therefore, we aim to address:

IL-18-responsive immune cells across blood and lesional AD skin The inflammatory cytokine milieu shaped by IL-18 The neutralization of IL-18 as a therapeutic strategy for AD
You will work with primary human T cells from PBMCs and skin, using flow cytometry, transcriptomic profiling (single-cell RNA sequencing), multiplex cytokine assays, and human skin explant models to clarify IL-18's role and therapeutic potential in AD.

Your Profile

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European academic degree in natural sciences (MSc) acceptable for matriculation at a Swiss University Fluent in English Dedicated to science and academia Theoretical & practical skills in immunology, molecular, & cellular biology

What we offer

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Our team offers a dynamic and aspiring translational research environment Close collaborations with local and international laboratories guarantees access to state-of-the-art know-how and infrastructure

Your application should include

Curriculum vitae with a brief description of laboratory experience

First rate training and further education

Our university clinics and institutes are "A" grade training organisations Support with individual professional progression and career paths Competent onboarding


weiterbildung

First rate training and further education

Our university clinics and institutes are "A" grade training organisations Support with individual professional progression and career paths Competent onboarding


weiterbildung

Work-life balance

Part-time and job-sharing opportunities 16 weeks of maternity leave 3 weeks of paternity leave


worklife

Work-life balance

Part-time and job-sharing opportunities 16 weeks of maternity leave 3 weeks of paternity leave


worklife

Benefits and allowances

Continued wage and salary payments in case of illness or accident: 1st year 100 %, 2nd year 80 % 100 % of the daily sickness benefit insurance premium Generous child, education and family allowances


sozialleistungen

Benefits and allowances

Continued wage and salary payments in case of illness or accident: 1st year 100 %, 2nd year 80 % 100 % of the daily sickness benefit insurance premium Generous child, education and family allowances


sozialleistungen
Location Inselspital, Universitatsspital
Organisation
Medical division internal medicine


Area Department of Dermatology
Workload
100 %


Start
Entry as of November 1, 2025, or upon agreement

temporary for 4 years


Reference
18337


Type of Contract
Temporary


Work Location
Inselspital, Universitatsspital Bern

Freiburgstrasse, CH-3010 Bern

Schweiz



For further information, please contact

Prof. Dr. med. Dr. phil. Christoph Schlapbach

Professor of Department of Dermatology,


+41316325402
Email