SNF-funded research project investigating the gut microbiota to develop innovative microbiome-based therapies for methylmalonic aciduria, a rare inborn error of metabolism
Your responsibilities
You design and perform experiments using germ-free and gnotobiotic mouse models to dissect microbiota-host interactions.
Perform stable isotope tracing, metabolomics, and LC-MS/MS analysis to track nutrient flux and disease biomarkers.
By integrating multi-omics datasets, you uncover mechanisms linking microbiota composition to disease severity.
You collaborate closely with experts in microbiome engineering and clinical metabolism.
contribute to scientific publications and present results at national and international conferences.
Your profile
PhD applicants: Master's degree in microbiology, molecular biology, or related field
Postdoctoral applicants: PhD in microbiology, molecular biology, or related field
Strong expertise in gnotobiotic/germ-free mouse models and host-microbe interactions
Experience with metabolomics, or mass spectrometry is highly desirable
Excellent organizational skills and ability to work in a multidisciplinary team
Strong communication skills in English
Kinderspital Zurich as an employer
Kinderspital Zurich is the largest university children's hospital in Switzerland with about 2,500 employees, and is one of the leading centres for paediatric and youth medicine in Europe. Although the hospital may be big, it's the little ones that count: up to 100,000 patients are cared for each year across 47 faculties, where we do everything in our power to ensure their well being. 'Kispi' not only offers cutting-edge devices and the highest quality of care, but also a good sense of interpersonal issues. Alongside its comprehensive range of paediatric medicine and surgery facilities, the children's hospital also offers a unique rehabilitation centre and a research centre.
Based on the SNF classification or individual salary assessment.