Job Description

Institute of Laboratory Animal Science (LTK)

Postdoctoral Fellow in Antigen-Specific Tolerance 80 - 100 %

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Start of employment ASAP, temporary
www.ltk.uzh.ch/en.html

Your responsibilities

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Peptide-red blood cells (pcRBC) are an antigen-specific therapy for the treatment of Multiple Sclerosis (MS), currently undergoing clinical testing. This postdoc position focuses on characterizing tolerance mechanisms induced by pcRBC in experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis. The project extends previously established foundations by defining the spatial organization of immunoregulatory microenvironments and the molecular mechanisms underlying antigen-specific suppression of pathogenic T-cell responses.

Your profile

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We seek candidates with a PhD in immunology, biology, neuroscience, or a related field who have demonstrated expertise in autoimmune disease animal models, particularly EAE or similar in vivo inflammatory models. You should have a strong background in flow cytometry, including multi-parameter analysis and cell sorting, along with experience in histological techniques and immunofluorescence microscopy. Proficiency in molecular biology methods, including RNA isolation, qPCR, and transcriptomic data analysis, is required. Also, prior work with primary cell cultures and ex vivo systems is expected. Your publication record should demonstrate experimental rigor and scientific writing ability. English fluency is mandatory.

What we offer

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Work-Life Balance

Flexible working models (such as part-time positions, mobile working, job-sharing) Childcare at the kihz foundation of UZH and ETH

Learning and Development

Wide range of continuing education courses of UZH and the Canton of Zurich Language Center run jointly with ETH Zurich

Food

Food and drinks at reduced prices in the UZH cafeterias Lunch-Check-card with UZH contribution

Healthcare

Special conditions on the Academic Sports Association ASVZ Free seasonal flu vaccinations Rest and relaxation at the quiet room in the university tower

Discounts

Private traffic: Carsharing, rent a vehicle, parking space Digitalization: Hardware, software, mobile phone subscriptions Special conditions on hotel reservations

Conditions of Employment

Policies of the UZH Most UZH staff are employed according to public law

International Services

Support for people from outside Switzerland

Campuses

Campuses Zurich City, Zurich Irchel, Oerlikon and Schlieren Sites Zurich West, Old Botanical Garden, Botanical Garden and Lengg

Location

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Institute of Laboratory Animal Science (LTK)

Wagistrasse 12, 8952 Schlieren, Switzerland

Further information

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Questions about the job

Prof. Thorsten Buch

Institut Manager

Questions about the application procedure

Gili Orpeli

Personalverantwortlich

Working at UZH

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The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!