Job Description

Department of Chemistry

PhD student - Development and application of site-specific phospho-encoding systems 80 %

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Start of employment as soon as possible
We are a newly established research group at the University of Zurich, focusing on the structural effects of posttranslational modifications within intrinsically disordered proteins. Our work combines biomolecular NMR with interdisciplinary approaches to answer fundamental questions in structural biology.



We believe that open communication, integrity, and mutual respect are the foundation of excellent research. Our goal is to foster a positive and inclusive work culture where every member feels valued and encouraged to contribute their ideas. Candidates should enjoy working collaboratively and be motivated to engage in interdisciplinary science.



Further information about our research can be found on our website.

Your responsibilities

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You will develop and apply innovative genetic code expansion tools to achieve site-selective incorporation of la-beled phospho-tyrosine. Your tasks will encompass utilization of state-of-the-art bionformatic tools for protein design, perform high-throughput cell uptake tests, perform selection assays and express, purify and analyze tar-get model proteins.

Your profile

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Requirements:A first-class Master's degree in chemistry, biochemistry, bioinformatics or a related field, awarded prior to the start of the contract or soon to be finished Background in protein design, computational biology or related field Working knowledge in at least one relevant coding language (Python, R, or C++) Excellent communication skills and excellent command of English, both spoken and written

Desirable:Experience in sterile cell culturing technique Familiarity with protein expression and purification Interest in protein biophysics and structural biology

Information on your application

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Please submit your application by 15th of October 2025, including a cover letter, a CV and the contact details of two references. Short-listed applicants will be interviewed either in person or via a video call.

What we offer

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Work-Life Balance

Flexible working models (such as part-time positions, mobile working, job-sharing) Childcare at the kihz foundation of UZH and ETH

Learning and Development

Wide range of continuing education courses of UZH and the Canton of Zurich Language Center run jointly with ETH Zurich

Food

Food and drinks at reduced prices in the UZH cafeterias Lunch-Check-card with UZH contribution

Healthcare

Special conditions on the Academic Sports Association ASVZ Free seasonal flu vaccinations Rest and relaxation at the quiet room in the university tower

Discounts

Private traffic: Carsharing, rent a vehicle, parking space Digitalization: Hardware, software, mobile phone subscriptions Special conditions on hotel reservations

Conditions of Employment

Policies of the UZH Most UZH staff are employed according to public law

International Services

Support for people from outside Switzerland

Campuses

Campuses Zurich City, Zurich Irchel, Oerlikon and Schlieren Sites Zurich West, Old Botanical Garden, Botanical Garden and Lengg

Location

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Department of Chemistry

Winterthurerstrasse 190, 8057 Zurich, Switzerland

Further information

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Questions about the job

Prof. Dr. Ricarda Torner

Assistant Professor

Working at UZH

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The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer!